Business Portfolio

Greater St. Louis is home to 18 Fortune 1000 companies, nine of which are in the Fortune 500.  We’re also home to some of the country’s largest privately held companies, including Enterprise Holdings and World Wide Technology; along with several firms consistently ranked among the “Best Companies to Work For.” 

Many of our businesses are at the epicenter of today’s most pressing topics – such as Monsanto delivering solutions to feed a growing planet; or Express Scripts and Centene leading efforts to lower the cost of healthcare.  But, it’s not just the biggest companies making their mark on this stage – the business incubators, accelerators, mentoring programs and pipelines are full of the next generation of companies that will make their mark on St. Louis, and quite possibly the world.  

Each year the St. Louis Business Journal celebrates the 25 fastest-growing companies in the St. Louis region.  These are some of the companies reshaping our community, and we’re pleased to share this overview and company listing with you.